I suspect no one of those companies are designed to be profitable ever.
Perhaps they have big losses because they sell below cost to gain traction.
All European countries fit in Brazil, Russia, Africa or Australia,
If you want to replicate a big success in Brazil, it will be as hard as the same to replicate it in all European countries, but in this case with 1/8 of population and the majority of the persons DO NOT own or WILL NOT use a credit/debit card to buy online! They will prefer to research online and then buy offline.
Many if not most; USA, Canada or European businesses models are unfeasible in Latin American countries! Perhaps the same situation for Africa, Russia or even Australia because transportation costs could be 10 times bigger than Europe.
As I was told once, all the domino should fall ... when they run out of money!